Sildenafil Alternatives Compared - Drugs.com (2024)

Prescription only

Sildenafil is used to treat erectile dysfunction (ED) and to reduce blood pressure in pulmonary arterial hypertension (PAH). It is taken when needed for ED and daily for PAH. A headache, stomach...View more

Prescription only

Cialis is used to treat erectile dysfunction (ED) and to reduce symptoms of benign prostatic hyperplasia (BPH). One 'as needed' tablet lasts for 36 hours or Cialis is available as a lower dosage...View more

Prescription only

Viagra is used to treat erectile dysfunction (ED), but will not have any effect in the absence of sexual stimulation. A headache, stomach upsets, and flushing are the main side effects. Prescribed...View more

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Popular comparisons

  • Sildenafil vs buspirone
  • Sildenafil vs tadalafil
  • Sildenafil vs Cialis
  • Sildenafil vs Viagra
  • Sildenafil vs Revatio
More aboutSildenafilMore aboutCialis(tadalafil)More aboutViagra(sildenafil)Ratings & Reviews

Sildenafil has an average rating of8.3 out of 10 from a total of495 ratings on Drugs.com.79% of reviewers reported a positive effect, while 12% reported a negative effect.

Cialis has an average rating of8.5 out of 10 from a total of547 ratings on Drugs.com.83% of reviewers reported a positive effect, while 9% reported a negative effect.

Viagra has an average rating of8.5 out of 10 from a total of255 ratings on Drugs.com.83% of reviewers reported a positive effect, while 9% reported a negative effect.

View all 495 reviews

View all 547 reviews

View all 255 reviews

Drug Class
  • Agents for pulmonary hypertension
  • Impotence agents
  • Impotence agents
  • Impotence agents
Side Effects

See also: sildenafil side effects in more detail.

See also: Cialis side effects in more detail.

See also: Viagra side effects in more detail.

Generic Availability

Lower cost generic

Lower cost generic approved

Lower cost generic approved

Pricing and Coupons* Prices are without insurance
Quantity2 tablet
Dosage100 mg
Per Unit*$4.83 - $16.06
Cost*$9.66 - $32.11

View all sildenafil prices

Quantity30 tablet
Dosage20 mg
Per Unit*$59.60
Cost*$1,788.08

View all Cialis prices

Quantity30 tablet
Dosage100 mg
Per Unit*$92.38
Cost*$2,771.36

View all Viagra prices

Get free Discount Card

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Dosage Forms Available
  • Intravenous solution
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet
  • Oral tablet
Brand NamesLiqrev, Revatio, ViagraOther tadalafil brands include: Adcirca, Alyq, TadliqOther sildenafil brands include: Liqrev, RevatioHalf LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

4 hours

17.5 hours

4 hours

CSA Schedule **View glossary of terms

N

Not a controlled drug

Is not subject to the Controlled Substances Act.

N

Not a controlled drug

Is not subject to the Controlled Substances Act.

N

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

B

Category BNo proven risk in humans

See the full pregnancy warnings document.

B

Category BNo proven risk in humans

See the full pregnancy warnings document.

B

Category BNo proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 335 drugs are known to interact with sildenafil:

  • 38 major drug interactions (139 brand and generic names)
  • 293 moderate drug interactions (908 brand and generic names)
  • 4 minor drug interactions (42 brand and generic names)

A total of 309 drugs are known to interact with Cialis:

  • 33 major drug interactions (139 brand and generic names)
  • 178 moderate drug interactions (514 brand and generic names)
  • 98 minor drug interactions (279 brand and generic names)

A total of 335 drugs are known to interact with Viagra:

  • 38 major drug interactions (139 brand and generic names)
  • 293 moderate drug interactions (908 brand and generic names)
  • 4 minor drug interactions (42 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • If you are receiving therapy with sildenafil you should avoid the regular consumption of large...View more

  • Sildenafil can lower blood pressure, and combining it with alcohol may further increase this...View more

  • Tadalafil can lower blood pressure, and combining it with alcohol may further increase this effect...View more

  • If you are receiving therapy with sildenafil you should avoid the regular consumption of large...View more

  • Sildenafil can lower blood pressure, and combining it with alcohol may further increase this...View more

Disease Interactions
  • Cardiovascular disease
  • Priapism
  • Alcoholism
  • Hearing loss
  • Liver disease
  • Seizure disorders
  • sickle cell disease
  • Bleeding disorders
  • Renal dysfunction
  • Visual disorders
  • Cardiovascular disease
  • Renal dysfunction
  • Pulmonary disease
  • Priapism
  • Alcoholism
  • Hearing loss
  • Liver disease
  • Retinitis pigmentosa
  • Seizure disorders
  • Cardiovascular disease
  • Priapism
  • Alcoholism
  • Hearing loss
  • Liver disease
  • Seizure disorders
  • sickle cell disease
  • Bleeding disorders
  • Renal dysfunction
  • Visual disorders
First Approval Date

March 27, 1998

November 21, 2003

March 27, 1998

WADA ClassView World Anti-Doping Agency classifications.

N/A

N/A

N/A

More Information
  • Side effects
  • Pregnancy warnings
  • Breastfeeding warnings
  • Dosage information
  • Drug images
  • Drug interactions
  • Support group
  • Pricing and coupons
  • Side effects
  • Pregnancy warnings
  • Breastfeeding warnings
  • Dosage information
  • Drug images
  • Drug interactions
  • Support group
  • Pricing and coupons
  • En Español
  • Side effects
  • Pregnancy warnings
  • Breastfeeding warnings
  • Dosage information
  • Drug images
  • Drug interactions
  • Support group
  • Pricing and coupons
  • En Español
Patient resources
  • Sildenafil uses
  • Advanced reading
  • Cialis uses
  • Viagra uses
Professional Resources
  • Monograph (AHFS)
  • Prescribing information
  • Prescribing information
  • Prescribing information
Related Treatment Guide
  • Erectile Dysfunction
  • Sexual Dysfunction - SSRI Induced
  • Pulmonary Arterial Hypertension
  • Benign Prostatic Hyperplasia
  • Erectile Dysfunction
  • Erectile Dysfunction
Sildenafil Alternatives Compared - Drugs.com (2024)

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